Pulmonary involvement in systemic sclerosis (scleroderma)

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Vascular involvement in systemic sclerosis (scleroderma)

Systemic sclerosis (SSc) is an acquired multiorgan connective tissue disease with variable mortality and morbidity dictated by clinical subset type. The etiology of the basic disease and pathogenesis of the systemic autoimmunity, fibrosis, and fibroproliferative vasculopathy are unknown and debated. In this review, the spectrum of vascular abnormalities and the options currently available to tr...

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Severe organ involvement in systemic sclerosis with diffuse scleroderma.

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Pulmonary Involvement in Systemic Sclerosis: Cases Review*

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Systemic Sclerosis (Scleroderma)

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Systemic Sclerosis (Scleroderma)

Systemic sclerosis (SSc) is a multisystem autoimmune disease in which there is increased fibroblast activity resulting in abnormal growth of connective tissue. This causes vascular damage and fibrosis. Fibrosis occurs in skin, the gastrointestinal (GI) tract, heart, lungs and other internal organs. Vascular manifestations include secondary Raynaud's phenomenon, ischaemia of extremities, pulmona...

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ژورنال

عنوان ژورنال: Arthritis & Rheumatism

سال: 1985

ISSN: 0004-3591,1529-0131

DOI: 10.1002/art.1780280706